Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?

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Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?

Maternal euthyroidism during pregnancy is crucial for normal development and, in particular, neurodevelopment of the foetus. Up to 3.5 percent of pregnant women suffer from hypothyroidism. Industrial use of various chemicals-endocrine disrupting chemicals (EDCs)-has been shown to cause almost constant exposure of humans with possible harmful influence on health and hormone regulation. EDCs may ...

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Thyroid Disrupting Chemicals

Endocrine disruptor compounds are exogenous agents able to interfere with a gland function, exerting their action across different functional passages, from the synthesis to the metabolism and binding to receptors of the hormone produced. Several issues, such as different levels and time of exposure and different action across different ages as well as gender, make the study of endocrine disrup...

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Pregnancy and thyroid cancer: ultrasound study of foetal thyroid.

Thyroid cancer is the most common endocrine malignancy, more frequently diagnosed in young women during childbearing age and approximately 10% of all thyroid cancers are diagnosed during pregnancy or in the early post-partum period. Thyroid cancer in young people has generally an excellent prognosis, and survival among women with thyroid cancer diagnosed during pregnancy may not differ from tha...

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Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes

BACKGROUND There is increasing evidence in humans and in experimental animals for a relationship between exposure to specific environmental chemicals and perturbations in levels of critically important thyroid hormones (THs). Identification and proper interpretation of these relationships are required for accurate assessment of risk to public health. OBJECTIVES We review the role of TH in ner...

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ژورنال

عنوان ژورنال: Journal of Thyroid Research

سال: 2011

ISSN: 2042-0072

DOI: 10.4061/2011/342189